You have to go to the Bus Terminal in downtown, the cost per person is around $27.00 in first class service and $35.00 in premier class, the trip takes is around 4h:20m. You have the option to buy your ticket to the CAME terminal which is the one located in downtown Merida, if you wnat to go to the hotel zone of Merida then buy your ticket to the Fiesta Americana terminal which is very near to the main hotels and the Paseo de Montejo avenua.